What to Look for in a Mesothelioma Specialist
Medical Oncologist
Your medical oncologist manages chemotherapy, immunotherapy, and systemic treatments. Look for:
- Active involvement in mesothelioma clinical trials (indicates current expertise)
- Affiliation with an NCI-designated comprehensive cancer center
- Published research on mesothelioma treatment (search their name on PubMed)
- Experience with immunotherapy combinations (Opdivo/Yervoy, Keytruda)
Thoracic Surgeon (Pleural Mesothelioma)
For pleural mesothelioma surgery (EPP or P/D), volume matters enormously. The surgeon should:
- Have performed more than 20–30 mesothelioma resections — ask directly
- Have trained at or collaborated with a high-volume center (Brigham, MSK, MD Anderson)
- Offer both EPP and P/D options and discuss the choice with you
- Work as part of a true multidisciplinary mesothelioma team, not just as an individual surgeon
Peritoneal Surgeon (Peritoneal Mesothelioma)
Cytoreductive surgery + HIPEC requires specialized training. Ask:
- How many HIPEC procedures do you perform per year? (50+ is ideal)
- What is your complete cytoreduction rate? (goal is >80%)
- Do you have a dedicated peritoneal surface malignancy program?
Questions to Ask at Your First Appointment
- What is my specific diagnosis (cell type, stage, laterality)?
- Am I a surgical candidate? Why or why not?
- What is the recommended first-line treatment, and what is the evidence base?
- Are there clinical trials I qualify for at this center or elsewhere?
- What would you recommend if I were your family member?
- Can I get my pathology slides reviewed by your pathologist?
- What is your center’s volume of mesothelioma cases per year?
- Who else is on the multidisciplinary team, and when do they meet?
Specialist Centers by Region
| Region | Center | Specialty |
|---|---|---|
| Texas / South Central | MD Anderson Cancer Center, Houston | Surgery, immunotherapy, HIPEC, trials |
| Northeast / New England | Brigham and Women’s / Dana-Farber, Boston | Pleural surgery, surgical volume leader |
| New York Metro | Memorial Sloan Kettering, NYC | Surgery, immunotherapy, high volume |
| Mid-Atlantic | Penn Medicine, Philadelphia | CAR-T trials, TTFields, surgery |
| Southeast | Moffitt Cancer Center, Tampa | Surgery, immunotherapy, trials |
| Midwest | University of Chicago / Mayo Clinic | Multidisciplinary, HIPEC, trials |
| Pacific Coast | UCLA / UCSF / UC San Diego | Surgery, immunotherapy, active trial programs |
| Pacific Northwest | University of Washington Medical Center | Thoracic oncology, trial access |